Congratulations to Pariya Salami and the team on their recent publication entitled “Quantifying seizure termination patterns reveals limited pathways to seizure end” in the journal Neurobiology of Disease! The study involves looking at the voltage signals at the end of the seizure to examine seizure termination pattern across 710 seizures recorded from 104 patients. They found that most seizures end synchronously, and show block-like termination patterns, often terminating with burst suppression regardless of if they are focal versus generalized. Their work highlight a surprising finding in that, even though epilepsy is varied and complex with a number of causes and symptoms, there may be a limited number of ways that seizures end. This could have significant implications for therapies in interrupting or stopping seizures.
